After getting H1N1, falling ill with H5N1 seems rather Super-fluous.
People who just got off airplanes are more susceptible to the flew.
Glaucoma is a terrible de-sees.
The Black Death was the best disease. Any attempts to replicate it are just plague-iarism.
Some grievous afflictions could benefit from better PR branding. E.g., have you heard about the exciting new disease, Übercoolosis?
When I found out who was defecating in the water supply, I was all hot under the cholera.